Phenylamino isothiazole carboxamidines as MEK inhibitors
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United States of America Patent
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Jan 26, 2010
Grant Date -
Dec 11, 2008
app pub date -
Jul 11, 2008
filing date -
Jan 20, 2005
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Abstract
The invention concerns compounds which inhibit MEK and which have activity as anti-neoplastic agents. These compounds include N-substituted-3-hydroxy-5-arylamino-isothiazole-4-carboxamidines. Also included are the tautomeric isothiazol-3(2H)-ones.
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