Bioabsorbable elastomeric polymer networks, cross-linkers and methods of use
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United States of America Patent
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Jan 19, 2010
Grant Date -
Oct 8, 2009
app pub date -
Mar 28, 2008
filing date -
Mar 30, 2007
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Abstract
The invention provides elastomeric polymer networks and semi-interpenetrating networks in which a linear PEA, PEUR or PEU polymer is crosslinked by ester or alpha-amino-acid containing cross-linkers that polymerize upon exposure to active species. Bioabsorbable elastomeric internal fixation devices fabricated using such polymer networks and semi-interpenetrating networks are useful for in vivo implant and delivery of a variety of different types of molecules in a time release fashion. Alpha-amino-acid containing ester amide cross-linkers are also provided by the invention.
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