Soluble, stable and concentrated pharmaceutical composition compromising ritonavir and process for preparing thereof
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United States of America Patent
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Dec 15, 2009
Grant Date -
Nov 10, 2005
app pub date -
Jun 12, 2003
filing date -
Jun 12, 2002
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Abstract
The present invention describes a soluble stable pharmaceutical composition for the administration of HIV protease inhibitors. More specifically the composition comprises a solution of an HIV protease inhibitor in a combination of suitable pharmaceutical organic solvents, a surfactant and a bioavailability enhancer. It is also described a process for the obtainment of concentrated pharmaceutical compositions used in the administration of HIV protease inhibitors compounds. The composition of the present invention is suitable for the preparation of oral solutions for the administration of active drugs and for the encapsulation in hard gelatin capsules or soft gelatin capsules.
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