Methods and compositions for inhibiting angiogenesis
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United States of America Patent
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Dec 1, 2009
Grant Date -
Jun 7, 2007
app pub date -
Jan 5, 2007
filing date -
Sep 1, 2000
priority date (Note) -
Expired
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Abstract
Methods for inhibiting angiogenesis in endothelial cells and selectively inducing apoptosis in endothelial cells via compounds which binds annexin II are provided. These compounds and methods for using these compounds are useful in the treatment of diseases or disorders characterized by unwanted angiogenesis. Also provided are pharmaceutical compositions containing a compound which binds annexin II and a pharmaceutically acceptable vehicle and methods for identifying such compounds.
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