Method for creating perfusable microvessel systems
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United States of America Patent
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Nov 24, 2009
Grant Date -
Sep 27, 2007
app pub date -
Mar 24, 2006
filing date -
Mar 24, 2006
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Abstract
Microvessel networks are produced in vitro from tissue-engineered parent vessels sprouting into a supporting matrix, as for example gels, of extracellular matrix proteins. The microvessel systems are integrated into devices that allow for controlled perfusion with fluids. The vessels may include cells from one cell type, for example, endothelial cells, or from combinations of two or more cell types.
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