Method and apparatus for enhanced estimation of an analyte property through multiple region transformation
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United States of America Patent
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Nov 17, 2009
Grant Date -
Jul 7, 2005
app pub date -
Oct 29, 2004
filing date -
Mar 7, 2003
priority date (Note) -
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Abstract
The invention comprises transformation of a section of a data block independently of the transformation of separate or overlapping data blocks to determine a property related to the original matrix, where each of the separate or overlapping data blocks are derived from an original data matrix. The transformation enhances parameters of a first data block over a given region of an axis of the data matrix, such as signal-to-noise, without affecting analysis of a second data block derived from the data matrix. This allows for enhancement of analysis of an analyte property, such as concentration, represented within the original data matrix. A separate decomposition and factor selection for each selected data matrix is performed with subsequent score matrix concatenization. The combined score matrix is used to generate a model that is subsequently used to estimate a property, such as concentration represented in the original data matrix.
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