GTPase inhibitors and use thereof for controlling platelet hyperactivity

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7612080
APP PUB NO 20060135542A1
SERIAL NO

11283556

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The preferred embodiments generally relate to methods and compositions that affect the GTP-binding activity of members of the Rho family GTPases, preferably Rac (Rac1, Rac2 and/or Rac3), such compositions include compounds that modulate the GTP/GDP exchange activity, along with uses for the compounds including screening for compounds which recognize Rac GTPase, and methods of treating pathological conditions associated or related to a Rho family GTPase, including Rac. The preferred embodiments also relate to methods of using such compounds, or derivatives thereof, e.g., in therapeutics, diagnostics, and as research tools.

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Patent Owner(s)

Patent OwnerAddress
GIRINDUS AMERICA INC8560 READING ROAD CINCINNATI OH 45215

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Akbar, Huzoor Athens , US 1 7
Mazur, Wieslaw Adam Mason , US 20 49
Williams, David A Cincinnati , US 145 2140
Zheng, Yi Cincinnati , US 394 5149

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