Mesostructured silica/block copolymer monoliths as a controlled release device and methods of manufacture
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United States of America Patent
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Nov 3, 2009
Grant Date -
Feb 16, 2006
app pub date -
Aug 12, 2005
filing date -
Aug 16, 2004
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Abstract
The invention comprises the design, synthesis, and characterization of mesostructured silica/block copolymer composite monoliths as controlled release systems. The controlled release function is based on the formation of mesostructured silica/block copolymer architectures via surfactant-templated sol-gel processing. Multi-layered or gradient monoliths are produced by layer-by-layer sol-gel processing to provide pulsed and programmed release characteristics. A simple, rapid route to prepare combinatorial compositional monolith libraries provides high-throughput synthesis and rapid screening of the release characteristics of the monoliths.
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