VEGFR-3 inhibitor materials and methods
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United States of America Patent
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Nov 3, 2009
Grant Date -
Nov 7, 2002
app pub date -
Jan 15, 2002
filing date -
Jan 17, 2001
priority date (Note) -
Expired
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Abstract
The present invention relates to the diagnosis, evaluation, and therapeutic intervention of disorders mediated by the activity of cell surface receptor VEGFR-3, which activity often is stimulated by VEGFR-3 ligands VEGF-C and VEGF-D. More particularly, the present invention identifies novel methods and compositions for the inhibition of VEGF-C/D binding to VEGFR-3. The compositions of the present invention will be useful in the inhibition of angiogenesis and lymphangiogenesis.
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