-antagonistic activity
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United States of America Patent
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Oct 27, 2009
Grant Date -
Nov 8, 2007
app pub date -
Nov 3, 2005
filing date -
Sep 21, 2001
priority date (Note) -
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Abstract
The present invention relates to a group of novel 4,5-dihydro-1H-pyrazole derivatives which are potent cannabinoid (CB.sub.1) receptor antagonists with utility for the treatment of diseases connected with disorders of the cannabinoid system. The compounds have the general formula (Ia) or (Ib) ##STR00001## wherein the symbols have the meanings given in the specification. The invention also relates to methods for the preparation of these compounds, and to pharmaceutical compositions containing one or more of these compounds as an active component.
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