Modulation of the phospholipase A2 pathway as a therapeutic

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United States of America Patent

PATENT NO 7605149
SERIAL NO

09743781

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Abstract

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There is provided a method of modifying vasoactivity by regulating a soluble Aβ pro-inflammatory pathway. Also provided is a method of modifying inflammatory reactions in microglia and neurons by regulating a soluble Aβ pro-inflammatory pathway. A method of treating patients with vascular disease by modifying an intracellular soluble Aβ pro-inflammatory pathway is also provided. A pharmaceutical composition consisting essentially of an effective amount of a soluble Aβ pro-inflammatory pathway regulator in a pharmaceutically effective carrier is also provided.

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Patent Owner(s)

Patent OwnerAddress
ALZHEIMER'S INSTITUTE OF AMERICA INCBLOOMINGTON IL 61701

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Mullan, Michael J Tampa , US 20 128
Paris, Daniel Tampa , US 29 71
Town, Terrence C Lutz , US 9 64

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