[1,2,4]triazolo[1,5,a]pyrimidin-2-ylurea derivative and use thereof
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United States of America Patent
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Oct 6, 2009
Grant Date -
Jan 11, 2007
app pub date -
Jun 2, 2004
filing date -
Jun 3, 2003
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Abstract
Novel [1,2,4]triazolo[1,5-a]pyrimidine derivative of the general formula (1): (1) its prodrug or a pharmaceutically acceptable salt thereof, which exhibits an antigen presentation inhibiting activity and is useful as a preventive and/or therapeutic agent for immunological rejection and/or graft versus host reaction in organ/bone marrow transplant, autoimmune disease, allergic disease and/or inflammatory disease and also useful as an anticancer drug or as an immunological tolerance inducer for transplanted organ/transplanted bone marrow.
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