Highly active xylose reductase from Neurospora crassa
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United States of America Patent
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Sep 22, 2009
Grant Date -
Oct 2, 2008
app pub date -
May 19, 2008
filing date -
Jun 15, 2004
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Abstract
as a His-tag fusion protein and subsequently purified in high yield. This xylose reductase was shown to have a high turnover rate and catalytic efficiency, high stability at room temperature, broad pH profile, and a preference of NADPH over NADH. This enzyme is utilized in production of xylitol and other sugar alcohols such as sorbitol and also in the metabolic enhancement of organisms used for fermentation of plant biomass into ethanol.
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