3′-prodrugs of 2′-deoxy-β-L-nucleosides
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United States of America Patent
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Sep 8, 2009
Grant Date -
May 26, 2005
app pub date -
Oct 25, 2004
filing date -
Jun 15, 2000
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Abstract
The present invention relates to compounds, compositions and methods for the treatment of a host infected with a hepatitis B virus. Specifically, compound and compositions of 3′-esters of 2′-deoxy-β-L-pyrimidine nucleosides are disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents. Compound and compositions of 3′,5′-diesters of 2′-deoxy-β-L-pyrimidine nucleosides are also disclosed, which can be administered either alone or in combination with other anti-hepatitis B agents.
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