Cripto-specific antibodies

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7582299
APP PUB NO 20050255117A1
SERIAL NO

10945853

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The invention provides Cripto-specific antibodies, or biologically functional fragments thereof, and uses thereof. Antibodies which bind Cripto and inhibit Cripto activity are provided. Antibodies which bind Cripto and inhibit the interaction between Cripto and ALK4 and/or between Cripto and Activin B are provided. Antibodies which bind Cripto and inhibit tumor growth are also provided. Antibodies which bind Cripto, inhibit Cripto activity, and inhibit tumor growth are also provided. The invention also provides methods of using these antibodies in therapeutic, diagnostic, and research applications.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

Patent OwnerAddress
BIOGEN MA INC225 BINNEY STREET CAMBRIDGE MA 02142

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Adkins, Heather Somerville , US 1 1
Miklasz, Steven Donald Upton , US 1 10
Rayhorn, Paul Foxboro , US 8 71
Sanicola-Nadel, Michele Winchester , US 24 368
Schiffer, Susan Gail Lexington , US 7 36
Williams, Kevin P Chapel Hill , US 15 104

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation