Anti-A33 antibody

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United States of America Patent

PATENT NO 7579187
APP PUB NO 20070141054A1
SERIAL NO

11629779

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention provides: an antibody or a antibody fragment thereof, which can bind to A33, which specifically attacks A33-expressing tumor cells with the use of ADCC and CDC based on the immune system, and for which no HAHA is produced; and a preventive or therapeutic agent for various malignant tumors including solid tumors that are currently treated with difficulty, which contains the antibody or an antibody fragment thereof. Specifically, the antibody or a functional fragment thereof is capable of binding to A33 and is produced by a hybridoma M10 (accession No. FERM BP-10107), M96 (accession No. FERM BP-10108), M165 (accession No. FERM BP-10106), N26 (accession No. FERM BP-10109), Q47 (accession No. FERM BP-10104), Q54 (accession No. FERM BP-10105), or R5 (accession No. FERM BP-10107). The preventive or therapeutic agent for tumors contains the antibody or a functional fragment thereof.

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Patent Owner(s)

Patent OwnerAddress
KYOWA HAKKO KOGYO CO LTDCHIYODA-KU TOKYO 100-8185

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kataoka, Shiro Takasaki , JP 20 224
Otani, Noriko Takasaki , JP 8 168
Tomura, Takafumi Takasaki , JP 4 35

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