Chromatin segmentation

Number of patents in Portfolio can not be more than 2000

United States of America Patent

PATENT NO 7574304
APP PUB NO 20050260583A1
SERIAL NO

10484530

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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A method of segmenting chromatin particles in a nucleus of a cell by locating regional minima in an image, computing a zone of influence (ZOI) around each regional minimum, and segmenting a single chromatin blob within each ZOI using a region growing procedure. The method can be used as the basis of a method of qualitatively characterizing the distribution of nuclear chromatin by computing features for individual chromatin particles. Chromatin features can be synthesized from the features of individual particles and particle features can be synthesized into nucleus features and slide features. The method is useful for detecting malignancy associated changes and changes during neoplasia. The method may also be used more generally to assess chromatin patterns in living cells during the cell life cycle. This makes it possible to measure alternations in the evolving patterns that result from pathological or environmental influences.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITY OF MELBOURNEGRATTAN STREET PARKVILLE VIC 3010
TELSTRA CORPORATION LIMITED242 EXHIBITION STREET MELBOURNE VICTORIA 3000 AUSTRALIA
UNIVERSITY OF QUEENSLAND THEST LUCIA 4072 QUEENSLAND BRISBANE 4072
UNIVERSITY OF SOUTH AUSTRALIANORTH TERRACE ADELAIDE SOUTH AUSTRALIA 5000
FLINDERS UNIVERSITYSTURT ROAD BEDFORD PARK SA 5042
UNIVERSITY OF ADELAIDEADELAIDE S A 5005
CEA TECHNOLOGIES INC65 GLADSTONE STREET FYSHWICK ACT 2
COMMONWEALTH OF AUSTRALIA(DEFENSE SCIENCE & TECHNOLOGY ORGANISATION)ESRL HEADQUARTERS BUILDING SALISBURY SOUTH AUSTRALIA 5108
COMPAQ COMPUTER AUSTRALIA PTY LTD139 FROME STREET ADELAIDE SA 50
RLM SYSTEMS PTY LTD23 LAKESIDE DRIVE BURWOOD EAST VIC 3

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Jackway, Paul Toowong, AU 3 67
Mehnert, Andrew St. Lucia, AU 1 6

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