IFBMs to promote the specific attachment of target analytes to the surface of orthopedic implants
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United States of America Patent
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Aug 11, 2009
Grant Date -
Mar 9, 2006
app pub date -
Jun 15, 2005
filing date -
Jun 16, 2004
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention provides an improved coating for surfaces of medical implants. The coating comprises at least one interfacial biomaterial (IFBM) which is comprised of at least one binding module that binds to the surface of an implant or implant-related material (“implant module”) and at least one binding module that selectively binds to a target analyte or that is designed to have a desired effect (“analyte module”). The modules are connected by a linker. In some embodiments, the IFBM coating acts to promote the recognition and attachment of target analytes to surface of the device. The IFBM coating improves the performance of implanted medical devices, for example, by promoting osteointegration of the implant.
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