Nanoparticle composite-coated glass microspheres for use in bioassays
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United States of America Patent
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Aug 11, 2009
Grant Date -
May 24, 2007
app pub date -
Nov 21, 2005
filing date -
Nov 21, 2005
priority date (Note) -
Expired
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Abstract
A microsphere for use in a bioassay comprising a glass core coated with a nanoparticle composite comprising a bioactive probe is provided. The nanoparticle composite coating enhances the density of bioprobe loading on the surface of the microspheres, resulting in enhanced dynamic range and sensitivity in bioassays. The particle may be used in detection systems where resonant light scattering properties of the particle are useful.
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