P-selectin ligand protein

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United States of America Patent

PATENT NO 7563760
APP PUB NO 20030018181A1
SERIAL NO

09935144

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Abstract

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A novel P-selectin ligand glycoprotein is disclosed, comprising the amino acid sequence set forth in SEQ ID NO:2 or by the amino acid sequence set forth in SEQ ID NO:4. DNA sequences encoding the P-selectin ligand protein are also disclosed, along with vectors, host cells, and methods of making the P-selectin ligand protein. Pharmaceutical compositions containing the P-selectin ligand protein and methods of treating inflammatory disease states characterized by P-selectin- and E-selectin-mediated intercellular adhesion are also disclosed.

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Patent Owner(s)

Patent OwnerAddress
GENETICS INSTITUTE LLC87 CAMBRIDGE PARK DRIVE CAMBRIDGE MASSACHUSETTS 02140 UNITED STATES OF AMERICA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chang, Xiao-Jia Newton Centre , US 16 332
Cumming, Dale Acton , US 9 244
Kumar, Ravindra Belmont , US 261 3174
Larsen, Glenn R Sudbury , US 44 513
Sako, Dianne S Boston , US 40 381
Shaw, Gray Cambridge , US 15 764
Veldman, Geertruida M Sudbury , US 41 1935

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