Amine derivative with potassium channel regulatory function, its preparation and use

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United States of America Patent

PATENT NO 7560473
APP PUB NO 20040266822A1
SERIAL NO

10466712

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Abstract

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The present invention provides amine derivatives represented by formula I, its isomers, racemes or optical isomers, pharmaceutical salts thereof, its amides or esters, pharmaceutical compositions containing said compounds and the preparation methods thereof. The invention also relates to the use of the above mentioned compounds in the preparation of drugs for the prophylaxis or treatment of cardiovascular diseases, diabetes, bronchial and urinary smooth muscle spasm as well as ischemic and anoxic nerve injury. The above compounds can be used to treat hypertension, angina diaphragmatic, myocardial infarction, congestive heart failure, arrhythmia, diabetes, spasmodic bronchial diseases, spasmodic bladder or ureter diseases, and depression.

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Patent Owner(s)

Patent OwnerAddress
INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P L ABEIJING 100850

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Cui, Wenyu Beijing , CN 3 30
Feng, Huasong Beijing , CN 1 30
Gao, Qixiu Beijing , CN 1 30
He, Huamei Beijing , CN 1 30
Hu, Gang Beijing , CN 102 837
Li, Fulin Beijing , CN 28 104
Liu, Lijun Beijing , CN 55 191
Liu, Wei Beijing , CN 1976 15390
Long, Chaoliang Beijing , CN 1 30
Lu, Xinqiang Beijing , CN 2 31
Tang, Xingchun Beijing , CN 1 18
Wang, Hai Beijing , CN 243 3208
Wang, Lin Beijing , CN 481 3933
Yan, Yuan Beijing , CN 45 193
Yang, Rifang Beijing , CN 7 108
Yun, Liuhong Beijing , CN 10 174
Zhao, Rusheng Beijing , CN 4 37

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