Carbamic acid compounds comprising a sulfonamide linkage as HDAC inhibitors
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United States of America Patent
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Jul 7, 2009
Grant Date -
Jul 3, 2008
app pub date -
Feb 13, 2008
filing date -
Sep 29, 2000
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Abstract
is an aryl leader group; and pharmaceutically acceptable salts, solvates, amides, esters, ethers, chemically protected forms, and prodrugs thereof. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit HDAC, and, e.g., to inhibit proliferative conditions, such as cancer and psoriasis.
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