Bicyclic compounds as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders
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United States of America Patent
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Jun 23, 2009
Grant Date -
May 25, 2006
app pub date -
Oct 11, 2005
filing date -
Oct 12, 2004
priority date (Note) -
Expired
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Abstract
The present invention discloses compounds of Formula I, d, m, n, p and r are herein defined, said compounds being novel antagonists for melanin-concentrating hormone (MCH), as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such MCH antagonists as well as methods of using them to treat obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes. An illustrative compound is shown below:
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