Chimeric nicotinic receptor subunits
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United States of America Patent
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Jun 23, 2009
Grant Date -
Nov 17, 2005
app pub date -
Jan 18, 2005
filing date -
Jul 19, 2002
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Abstract
A chimeric nAChR receptor subunit polypeptide having a substitution of at least about 15% of the native amino acid sequence of the subunit in the area of the C-terminal cytoplasmic domain is provided, as well as polynucleotides encoding the polypeptide. Vectors, host cells, and related methods for evaluating compounds are also provided.
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