Polyglycerol compositions for the protection of living systems from states of reduced metabolism
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United States of America Patent
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Jun 23, 2009
Grant Date -
Feb 2, 2006
app pub date -
Sep 23, 2005
filing date -
Nov 30, 1999
priority date (Note) -
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Abstract
Polyglycerol, lactose, and a combination of polyglycerol and lactose are effective at preserving cells, tissues, and organs from damage due to hypothermic, ischemic, or other metabolic impairment, and a mixture of polyglycerol plus lactose is particularly useful for the hypothermic storage of cells, tissues, and organs. The mixture of polyglycerol and lactose can be further improved by the addition of chondroitin sulfate, chlorpromazine, calcium, citrate, glutathione, adenine, glucose, magnesium, and a pH buffer.
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