]pyrimidin-6-one derivatives
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United States of America Patent
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Jun 16, 2009
Grant Date -
Apr 3, 2008
app pub date -
Oct 3, 2007
filing date -
Dec 19, 2003
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Abstract
The invention relates to a dihydrospiro-[cycloalkylamine]-pyrimidone derivative represented by formula (I) or a salt thereof:wherein: X, Y, R1, R2, R3, R4, o, m, n, p and q are as defined herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.
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