Aryl and heteroaryl compounds, compositions, and methods of use

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United States of America Patent

PATENT NO 7544699
APP PUB NO 20050059705A1
SERIAL NO

10913168

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention provides aryl and heteroaryl compounds, methods of their preparation, pharmaceutical compositions comprising the compounds, and their use in treating human or animal disorders. The compounds of the invention may be antagonists, or partial antagonist of factor IX and/or factor XI and thus, may be useful for inhibiting the intrinsic pathway of blood coagulation. The compounds may be useful in a variety of applications including the management, treatment and/or control of diseases caused in part by the intrinsic clotting pathway.

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Patent Owner(s)

Patent OwnerAddress
VTVX HOLDINGS I LLC4170 MENDENHALL OAKS PKWY HIGH POINT NC 27265

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Andrews, Robert C Jamestown , US 42 713
Behme, Christopher Jamestown , US 15 106
Christen, Daniel Peter Jamestown , US 5 335
Gohimmukkula, Devi Reddy Jamestown , US 8 343
Guo, Xiao-Chuan High Point , US 9 271
Huang, Guoxiang Greensboro , US 16 634
Mjalli, Adnan M M Jamestown , US 93 1556
Rothlein, Robert Summerfield , US 41 496
Tyagi, Sameer High Point , US 6 336
Yaramasu, Tripura Greensboro , US 3 59

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