Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs as HSP90-inhibitors
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United States of America Patent
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Jun 9, 2009
Grant Date -
Oct 5, 2006
app pub date -
Mar 29, 2006
filing date -
Mar 30, 2005
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Abstract
Alkynyl pyrrolo[2,3-d]pyrimidines and related analogs are described and demonstrated to have utility as Heat Shock Protein 90 (HSP90) inhibiting agents used in the treatment and prevention of various HSP90 mediated disorders. Methods of synthesis and use of such compounds are also described and claimed.
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