Tet repressor-based transcriptional regulatory proteins
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United States of America Patent
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Jun 2, 2009
Grant Date -
Nov 6, 2003
app pub date -
Jun 5, 2003
filing date -
Jun 7, 1999
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Abstract
The present invention provides a panel of transcriptional activator fusion proteins which comprises both tetracycline controlled transactivator proteins and reverse tetracycline transactivator proteins. These transactivators have novel phenotypes such as altered basal transcriptional activity in the absence of doxycycline, altered induced transcriptional activity in the presence of doxycycline, or differential induction by tetracycline and analogs of tetracycline.
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