Diagnostic and prognostic compounds and method
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United States of America Patent
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May 19, 2009
Grant Date -
Aug 17, 2006
app pub date -
Mar 10, 2004
filing date -
Mar 10, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to a method of diagnosing bacterial or fungal sepsis in a subject, which method comprises the step of measuring the level of TREM-1-Ligand or TREM-1-Ligand nucleic acid in a biological sample obtained from said subject. The method can involve contacting said biological sample with a compound capable of binding TREM-1-Ligand and detecting the level of TREM-1-Ligand present in the sample by observing the level of binding between said compound and TREM-1-Ligand. Compounds, compositions and kits for use in the diagnosis of bacterial or fungal sepsis are also provided.
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