Modulators of coagulation factors with enhanced stability
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United States of America Patent
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May 12, 2009
Grant Date -
May 29, 2008
app pub date -
Oct 11, 2006
filing date -
Apr 22, 2004
priority date (Note) -
Expired
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Abstract
The invention provides improved nucleic acid ligands with enhanced stability that inhibit coagulation and improved modulators of the nucleic acids to provide ideal modulators of coagulation. These improved nucleic acids and modulators are particularly useful for inhibiting coagulation in a host undergoing a therapeutic regime such as surgery or coronary artery bypass.
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