Chromosome-based platforms
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United States of America Patent
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Apr 21, 2009
Grant Date -
Aug 18, 2005
app pub date -
Dec 6, 2004
filing date -
May 30, 2001
priority date (Note) -
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Abstract
Artificial chromosomes, including ACes, that have been engineered to contain available sites for site-specific, recombination-directed integration of DNA of interest are provided. These artificial chromosomes permit tractable, efficient, rational engineering of the chromosome for a variety of applications.
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