STAT3 activated stem cell
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United States of America Patent
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Mar 31, 2009
Grant Date -
Aug 21, 2003
app pub date -
Feb 18, 2003
filing date -
Feb 15, 2002
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Abstract
Stem cells modified to express activated form of STAT3 by genetic modification or protein delivery, and stem cells co-cultured with cells expressing activated form of STAT3 exhibit increased ex-vivo expansion and enhanced in-vivo regeneration accompanied by net increase in stem cell self-renewal as compared to control group.
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