Method for regulating immune function using the FOXP3 protein
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United States of America Patent
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Mar 24, 2009
Grant Date -
Sep 11, 2003
app pub date -
May 8, 2002
filing date -
May 8, 2001
priority date (Note) -
Expired
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Abstract
Isolated nucleic acid molecules are provided which encode Fkh.sup.sf, as well as mutant forms thereof. Also provided are expression vectors suitable for expressing such nucleic acid molecules, and host cells containing such expression vectors. Also provided are pharmaceutical compounds and methods of identifying such compounds that can modulate the immune system. In addition are provided methods for identifying proteins regulated by Scurfin (Fkh.sup.sf) and proteins that induce or inhibit Scurfin or Foxp3 expression.
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