Method for obtaining precursor Z and use thereof for the production of a means for therapy of human molybdenum cofactor deficiency
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United States of America Patent
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Mar 17, 2009
Grant Date -
Feb 15, 2007
app pub date -
Jan 31, 2006
filing date -
Jan 29, 2004
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Abstract
The invention relates to a method for obtaining the molybdopterin derivative precursor Z, wherein an over-production of precursor Z occurs in host organisms by recombinant expression of precursor Z synthesizing proteins. The invention further relates to the use of precursor Z for the production of a means for the therapy of human molybdenum cofactor deficiency and associated diseases, which may be directly or indirectly attributed to an altered molybdenum cofactor synthesis, whereby precursor Z is used as essential component of said therapy means.
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