Bicyclic pyrimidines and bicyclic 3,4-dihydropyprimidines as inhibitors of cellular proliferation

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United States of America Patent

PATENT NO 7501425
SERIAL NO

09623737

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Abstract

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This invention provides substituted pyrimido-pyrimidines that are useful for treating cell proliferative disorders, such as cancer and restenosis, as well as angiogenesis and atherosclerosis. The invention compounds have Formula I:The invention also provides pharmaceutical formulations comprising a compound of Formula I together with a pharmaceutically acceptable carrier, diluent, or excipient therefor, and a method for treating angiogenesis using said compounds.

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Patent Owner(s)

Patent OwnerAddress
WARNER LAMBERT COMPANYANN ARBOR MI

International Classification(s)

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  • 1999 Application Filing Year
  • A61K Class
  • 7992 Applications Filed
  • 3176 Patents Issued To-Date
  • 39.74 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances19992000200120022003200420052006200720082009201020112012201320142015201620170255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Dobrusin, Ellen Myra Ann Arbor , US 14 307
Hamby, James Marino Ann Arbor , US 12 354
Kramer, James Bernard Sylvania , US 32 185
Schroeder, Mel Conrad Dexter , US 10 331
Showalter, Howard Daniel Hollis Ann Arbor , US 20 516
Toogood, Peter Ann Arbor , US 12 103
Trumpp-Kallmeyer, Susanne A Moeindal , DE 2 65

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Patent Citation Ranking

  • 16 Citation Count
  • A61K Class
  • 64.41 % this patent is cited more than
  • 16 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges509253082135216811765452724174301 - 1011 - 2021 - 3031 - 4041 - 5051 - 6061 - 7071 - 8081 - 9091 - 100100 +02004006008001000120014001600180020002200240026002800

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