Method for cell selection
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United States of America Patent
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Mar 10, 2009
Grant Date -
Feb 10, 2005
app pub date -
May 12, 2004
filing date -
May 12, 2003
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Abstract
The invention relates to a method for the non-invasive selection of single living cells under gentle conditions from mixtures of cells or cell cultures with respect to a specific production performance. To this end, the concentration of substances produced by the individual cells which become enriched at the cell membrane, such as reporter gene products (GFP) or specifically secreted products, such as antibodies, is determined by fluorescence-microscopic detection methods.
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