Methods for treatment of thiol-containing compound deficient conditions
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United States of America Patent
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Mar 3, 2009
Grant Date -
Mar 16, 2006
app pub date -
Aug 24, 2005
filing date -
Oct 31, 2002
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Abstract
Methods for therapy of cystic fibrosis and other conditions are provided. The methods comprise one or more agents capable of increasing thiol-containing compound transport via a transporter system (i.e. ABC transporters such as MDR-1 or MRP-2) in cells. Other embodiments include the use of agents to modulate transport of thiol-containing compounds within the cell. Therapeutic methods involve the administration of such agents to a patient afflicted with cystic fibrosis and/or another condition responsive to stimulation of thiol-containing compound transport.
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