Costunolide derivatives
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United States of America Patent
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Feb 10, 2009
Grant Date -
Feb 28, 2008
app pub date -
Aug 14, 2007
filing date -
Aug 15, 2006
priority date (Note) -
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Abstract
A compound of the following formula:wherein X, Y, and Z are as defined herein. Also disclosed are methods for inhibiting TNFα expression, IL-1β expression, iNOS expression, and NF-κB activity and methods for treating autoimmune disease, cancer, or atherosclerosis with such a compound.
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