Nonsolvate-form crystal of polymethine compound and process for producing the same
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United States of America Patent
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Feb 3, 2009
Grant Date -
Apr 12, 2007
app pub date -
Nov 12, 2004
filing date -
Nov 21, 2003
priority date (Note) -
Expired
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Abstract
A novel nonsolvate-form crystal of polymethine compound is provided which has good stability in solution, shows a high gram extinction coefficient, is excellent in storage stability, is easy to handle and is highly sensitive to general-purpose semiconductor lasers.Thus is provided a nonsolvate-form crystal of polymethine compound of the formula (I) given below as well as a process for producing the nonsolvate-form crystal of polymethine compound of formula (I) which comprises reacting a polymethine ether compound of the formula (II) given below with hydrochloric acid or hydrobromic acid.(In the above formula, X represents Cl or Br.)(In the above formula, R represents an alkyl group, an alkoxyalkyl group or an optionally substituted aryl group.)
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