Substituted 4H-chromens, 2H-chromenes, chromans and analogs as activators of caspases and inducers of apoptosis and the use thereof

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United States of America Patent

PATENT NO 7476741
APP PUB NO 20050176750A1
SERIAL NO

10514426

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Abstract

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, A, B, X, Y, Z and dotted lines are defined herein. The present invention also relates to the discovery that compounds having Formula (I) are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.

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Patent Owner(s)

Patent OwnerAddress
CYTOVIA INCSAN DIEGO CA

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Attardo, Giorgio Laval, CA 29 249
Cai, Sui Xiong San Diego, US 124 1781
Denis, Real Montreal , CA 14 124
Jiang, Songchun San Diego, US 38 346
Rej, Rabindra Montreal , CA 11 136
Storer, Richard Pinner, GB 78 2192

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