Composition comprising a gastrin/CCK receptor ligand and an EGF receptor ligand
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United States of America Patent
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Jan 13, 2009
Grant Date -
Oct 19, 2006
app pub date -
Nov 14, 2005
filing date -
Jan 12, 2001
priority date (Note) -
Expired
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Abstract
Compositions and methods are provided for achieving in vivo islet cell regeneration in subjects with preexisting diabetes. The methods comprise short term treatment with a composition having a gastrin/cholecystokinin receptor ligand and an EGF receptor ligand. Treatment with such a composition for a short term resulted in a prolonged period of increased insulin release, decreased fasting blood glucose, and improved glucose tolerance, the prolonged efficacy, the period being considered from the time of cessation of treatment.
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