11β-benzaldoxime derivatives of D-homooestra-4,9-dien-3-ones
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United States of America Patent
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Jan 6, 2009
Grant Date -
Jun 28, 2007
app pub date -
Dec 7, 2006
filing date -
Dec 8, 2005
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Abstract
The present patent application relates to 11β-benzaldoxime derivatives of D-homooestra-4,9-dien-3-ones of formula I:Compounds of formula I bind more strongly to the glucocorticoid receptor than to the progesterone receptor and are effective antiglucocorticoids. According to the invention, they are suitable for the treatment and/or prevention of symptoms and/or diseases that are attributable to an androgen deficiency induced by glucocorticoids, especially cortisol.
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