Aldolase-inhibiting aromatic compounds

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United States of America Patent

PATENT NO 7470821
APP PUB NO 20070043002A1
SERIAL NO

10562251

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Abstract

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The invention relates to novel aldolase-inhibiting compounds that can be advantageously used as medicaments (in therapeutic doses), especially for treating certain cancers, due to the inhibition efficacy thereof. An inventive compound corresponds to general formula (I) wherein the aldehyde group (--CHO) and the phenol group (--OH) are linked to two carbon atoms adjacent to the same aromatic chain, i.e., the first aromatic chain, and R is a phosphate group or a phosphate group mimetic linked to a carbon atom of the second aromatic chain.

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Patent Owner(s)

Patent OwnerAddress
UNIVERSITE PAUL SABATIER TOULOUSE III31062 TOULOUSE CEDEX 9

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Azema, Laurent Auterive, FR 3 0
Blonski, Casimir Ramonville, FR 4 4
Dax, Chantal Toulouse, FR 2 0
Sygusch, Jurgen Montreal, CA 7 473

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