Process for decreasing aggregate levels of pegylated protein
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United States of America Patent
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Dec 30, 2008
Grant Date -
Apr 21, 2005
app pub date -
Sep 22, 2003
filing date -
Sep 20, 2002
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Abstract
The present invention is directed generally to recombinant methods for making a desired pegylated protein and pooling of same. The method(s) yield a polypeptide product containing reduced levels of aggregate thereof pooled to provide the desired pegylated isoforms thereof.
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