Therapeutic antibodies
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United States of America Patent
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Dec 16, 2008
Grant Date -
Dec 23, 2004
app pub date -
Oct 9, 2001
filing date -
Oct 9, 2000
priority date (Note) -
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Abstract
A pharmaceutical comprising a therapeutic protein that binds to a therapeutic target, the protein being modified with a compound that inhibits binding of the protein to the therapeutic target, the modified protein being effective for reducing an immune response against the protein and for producing a therapeutic effect by binding to the therapeutic target. The therapeutic protein may be an antibody that includes an antibody combining site that binds to the therapeutic target.
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