Monoclonal antibodies against the interferon receptor, with neutralizing activity against type I interferon

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United States of America Patent

PATENT NO 7465451
APP PUB NO 20070128701A1
SERIAL NO

11616564

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Abstract

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The invention relates to a monoclonal antibody directed against the human interferon class I receptor (IFN-R) characterized by the following properties: it recognizes the extracellular domain of the human IFN-R, and it has a neutralizing capacity against the biological properties of the human type I-IFN. It further concerns their use for the diagnosis.

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Patent Owner(s)

Patent OwnerAddress
E R SQUIBB & SONS L L CROUTE 206 AND PROVINCE LINE ROAD PRINCETON NJ 08540

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Benoit, Patrick Paris, FR 20 182
Maguire, Deborah Paris, FR 3 24
Meyer, Francois Paris, FR 11 193
Plavec, Ivan Fresnes, FR 22 230
Tovey, Michael Gerard Paris, FR 25 230

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