Methods and compositions for use in diagnosing and characterizing chronic immune disease
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United States of America Patent
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Dec 9, 2008
Grant Date -
May 19, 2005
app pub date -
Oct 12, 2004
filing date -
May 15, 2000
priority date (Note) -
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Abstract
Methods are provided for diagnosing and/or characterizing chronic immune disease activity in a subject. In the subject methods, a sample is obtained from a subject suspected of having or known to have a chronic immune disease. The sample is then assayed for the presence of low molecular actin fragments. The assay results are used to diagnose the presence of chronic immune disease activity and/or characterize chronic immune disease activity in the subject, e.g. to confirm an initial chronic immune disease diagnosis, to determine the stage of the disease, to monitor disease progression, to predict disease attacks, and the like. Also provided by the subject invention are kits for practicing the methods.
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