Homotrimeric extended OBG3 globular head and uses thereof
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United States of America Patent
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Dec 2, 2008
Grant Date -
Nov 9, 2006
app pub date -
May 26, 2003
filing date -
May 31, 2002
priority date (Note) -
Expired
status (Latency Note)
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Abstract
The present invention relates to the field of obesity research. Obesity is a public health problem that is serious and widespread. A compound, homotrimer of OBG3 polypeptide fragment comprising globular domain and all or part of OBG3 collagen-like region, has been identified that has utility for reducing body mass, for maintaining weight loss, and for treating obesity-related diseases and disorders. These obesity-related diseases and disorders include hyperlipidemias, atherosclerosis, diabetes, and hypertension.
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