Method of producing a compound by fermentation
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United States of America Patent
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Dec 2, 2008
Grant Date -
Jun 16, 2005
app pub date -
Aug 6, 2004
filing date -
Aug 8, 2003
priority date (Note) -
Expired
status (Latency Note)
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Abstract
During the production of a product compound by fermentation, the concentration of a precursor compound is maintained within a pre-selected concentration range by having an adsorbent resin in contact with the culture medium. The adsorbent resin reversibly adsorbs precursor compound and, as un-adsorbed precursor compound is converted to product compound, adsorbed precursor compound is released from the resin, thus maintaining the concentration of precursor compound within the pre-selected range.
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